Bartlett Publishing has put together several lists of books available from many various publishers which are essential reading for anyone interested in the topic. Check them out today!
You can view the articles from the blogs which preceded these at the following URLs:
Each specific base pair sequence of length n [i.e. the MicroRNA targets], has a probability of 1/n^4. An 8 pair sequence has a pobability of 1/4^8 or ~ 1/64000. To have two that match I think we need to multiply the probabilities of each. Get the drift? After seeing the same target sequence not a couple but hundreds of times, and in the protein target groups that give the right combinations for function, doesn’t design spring to your mind?